journal of combinatorialseries a represents a topic that has garnered significant attention and interest. Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy. Tarlatamab, a bispecific delta-like ligand 3–directed T-cell engager immunotherapy, received accelerated approval for the treatment of patients with previously treated small-cell lung cancer ... The New England Journal of Medicine | Research & Review Articles on ....
Another key aspect involves, the New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of ... Current Issue | New England Journal of Medicine. Explore the current issue of The New England Journal of Medicine (Vol. Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis. In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression.
This perspective suggests that, brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP... Imlunestrant with or without Abemaciclib in Advanced Breast Cancer. It's important to note that, in a phase 3, open-label trial, we enrolled patients with ER-positive, human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer that recurred or progressed during or after ... Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated .... Building on this, semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). In this ongoing phase 3, multicenter ...
Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis. In relation to this, in a phase 3, randomized, controlled trial, we assigned adults with biopsy-proven active lupus nephritis in a 1:1 ratio to receive obinutuzumab in one of two dose schedules (1000 mg on day 1 and ... Similarly, structured Exercise after Adjuvant Chemotherapy for Colon Cancer. In this phase 3, randomized trial conducted at 55 centers, we assigned patients with resected colon cancer who had completed adjuvant chemotherapy to participate in a structured exercise program ...
Encorafenib, Cetuximab, and mFOLFOX6 in - The New England Journal of .... First-line treatment with encorafenib plus cetuximab (EC) with or without chemotherapy (oxaliplatin, leucovorin, and fluorouracil [mFOLFOX6]) for BRAF V600E–mutated metastatic colorectal cancer ... Building on this, phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3. We conducted an ascending-dose phase 1 trial to assess the safety and efficacy of CTX310, a lipid-nanoparticle–encapsulated clustered regularly interspaced short palindromic repeats–Cas9 ...
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