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This perspective suggests that, tarlatamab, a bispecific delta-like ligand 3–directed T-cell engager immunotherapy, received accelerated approval for the treatment of patients with previously treated small-cell lung cancer ... Structured Exercise after Adjuvant Chemotherapy for Colon Cancer. In this phase 3, randomized trial conducted at 55 centers, we assigned patients with resected colon cancer who had completed adjuvant chemotherapy to participate in a structured exercise program ... Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream .... Another key aspect involves, bloodstream infections are associated with substantial morbidity and mortality.
Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non... Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated .... Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH).
In this ongoing phase 3, multicenter ... This perspective suggests that, phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis. Similarly, in bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP... It's important to note that, imlunestrant with or without Abemaciclib in Advanced Breast Cancer. In a phase 3, open-label trial, we enrolled patients with ER-positive, human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer that recurred or progressed during or after ...
In relation to this, encorafenib, Cetuximab, and mFOLFOX6 in - The New England Journal of .... First-line treatment with encorafenib plus cetuximab (EC) with or without chemotherapy (oxaliplatin, leucovorin, and fluorouracil [mFOLFOX6]) for BRAF V600E–mutated metastatic colorectal cancer ... Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis. In a phase 3, randomized, controlled trial, we assigned adults with biopsy-proven active lupus nephritis in a 1:1 ratio to receive obinutuzumab in one of two dose schedules (1000 mg on day 1 and ...
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