Esi 05 Camp Targetmol

Esi 05 Camp Targetmol Esi 05 (nsc 116966) is a specific 0.4 μm ic50 epac2 antagonist that blocks camp induced epac2 and rap1 activation. Description: esi 05 (nsc 116966) is a specific epac2 (exchange protein directly activated by camp 2) antagonist (ic50: 0.4 µm). esi 05 inhibits camp mediated activation of epac2, as well as eapc2, mediated rap1 activation.

Esi 05 Camp Inhibitor Cas 5184 64 5 Selleck Esi 05 inhibits camp mediated epac2 gef activity with an ic50 of 0.43 μm. esi 05 can be used for the research of diabetes, insulin secretion and neurological disorders. Bioactivity: esi 05 is a specific epac2 (exchange protein directly activated by camp 2) antagonist (ic50: 0.4 μm). esi 05 inhibits camp mediated activation of epac2, as well as eapc2, mediated rap1 activation. Esi 05 is an inhibitor of exchange protein activated by camp 2 (epac2) that inhibits camp induced epac2 guanine nucleotide exchange factor (gef) activity with an ic 50 value of 0.43 µm in a cell free assay. 1 it is selective for epac2 over epac1 and pka at 25 µm. Esi 05 is a potent eapc2 specific antagonist that inhibits camp mediated epac2 gef activity with apparent ic50 of 0.43 um. esi 05 inhibits rap1 activation mediated by eapc2, but not epac1.

Esi 08 Camp Targetmol Esi 05 is an inhibitor of exchange protein activated by camp 2 (epac2) that inhibits camp induced epac2 guanine nucleotide exchange factor (gef) activity with an ic 50 value of 0.43 µm in a cell free assay. 1 it is selective for epac2 over epac1 and pka at 25 µm. Esi 05 is a potent eapc2 specific antagonist that inhibits camp mediated epac2 gef activity with apparent ic50 of 0.43 um. esi 05 inhibits rap1 activation mediated by eapc2, but not epac1. Esi 05 (nsc 116966) is a specific epac2 (exchange protein directly activated by camp 2) antagonist (ic50: 0.4 μm). esi 05 inhibits camp mediated activation of epac2, as well as eapc2, mediated rap1 activation. powder: 20°c for 3 years | in solvent: 80°c for 1 year | shipping with blue ice shipping at ambient temperature. Esi 05 is a selective inhibitor against camp regulated guanine nucleotide exhange factor (gef) epac2 (exchange factor directly activated by camp 2) activation by targeting an epac2 specific allosteric site at the interface of the two camp binding domains. Stability and storage: esi 05 is chemically rather stable and does not need special care during handling or shipment. nevertheless, we recommend that the compound should be stored in the freezer ( 20° celsius necessary, 80° recommended), for longer storage periods preferably in freeze dried form. Esi 05 (nsc 116966) is a specific epac2 (exchange protein directly activated by camp 2) antagonist (ic50: 0.4 µm). esi 05 inhibits camp mediated activation of epac2, as well as eapc2, mediated rap1 activation.