Understanding 049 squid games requires examining multiple perspectives and considerations. I think I figured out what SCP-049’s pestilence is. SCP-049’s proxies are completely devoid of them yet 049 has stated that the loss of the individuality is a pity. While emotions are important to a personality, it isn’t required according to studies.
Emotions could be seen as the biggest plague of mankind as they are the driving force behind almost all conflict and suffering. A Complete Rework for SCP-049 : r/SCPSecretLab - Reddit. Additionally, successfully inspecting or performing surgery on a corpse heals SCP-049 for 75 Hume Shield. The purpose of this damage reduction is to allow SCP-049 hold his own against bigger groups of enemies.
SCP 049 Backstory/Origin : r/SCP - Reddit. SCP-049 used to be a perfectly normal human being living in the mid 1300s with a wife and children. It's important to note that, he is a plague doctor (old style mask) and after both of his children die from the plague, he runs out of town distraught and is on the verge of committing suicide. I think SCP-049 is severely misunderstood.

Why not communicate with 049 via intercom or some other technology? Another key aspect involves, and why cease the supply of corpses and animals to 049? I mean, we are trying to understand what this "Pestilence" is after all. I think the opposite should be done: constantly throw in living D class personnel to 049's chamber and let it do its thing!
This perspective suggests that, 049 is a normal human : r/SCP - Reddit. This all could point to the fact that 049 is a normal, baseline, non anomalous human doctor, who has been trying to prevent the spread of an anomalous disease for the last 500 years that causes aging and death as we know them. Assuming death is not actually a normal part of life, but the pestilence spread uncontrollably and the foundation simply decided to repeat what happened to colour to ... What connection does SCP-049-J have to SCP-049? If I’m correct the scp-049-J is the son of 049.

From another angle, there is a video about that on scp explained. Why do people ship SCP-049 and SCP-035? The original 049 file (SCP-049-ARC) has an addendum about what's implied to be an encounter between both. How can I deal with 049?
Another key aspect involves, : r/scpcontainmentbreach - Reddit. From another angle, i lock 049 into 914 or another key card door if I need to get away from him, it's effective untill he tps. You can keep him from tping by staying near the room you locked him in. So in one of the articles.. Is it canon that scp 049 and scp ...
Is it canon that scp 049 and scp 035 are In a relationship?

📝 Summary
As discussed, 049 squid games represents a valuable field that deserves consideration. In the future, further exploration on this topic may yield even greater knowledge and advantages.
If you're just starting, or knowledgeable, there's always more to discover in 049 squid games.