The subject of glp 1 use in pregnancy encompasses a wide range of important elements. Glucagon-like peptide-1 receptor agonist use in pregnancy: a review. GLP-1RA use, presumably through its effect on weight loss, leads to improved fertility, providing an opportunity to evaluate maternal, fetal, and neonatal risks. This review aims to summarize what is known in the literature about GLP-1RAs and pregnancy outcomes. Use of GLP1 receptor agonists in early pregnancy and reproductive .... The aim of this study was to assess the risks associated with GLP1-RA exposure during early pregnancy.
First Large Study of GLP-1 Receptor Agonists During Pregnancy. Recent results provided “reassuring” early evidence that taking noninsulin antidiabetic medications (ADMs) for type 2 diabetes—including glucagon-like peptide 1 (GLP-1) receptor agonists—during early pregnancy is not linked with a greater risk of major birth defects than taking insulin. Connection Between Pregnancies and GLP-1 Agonists. Researchers haven’t yet quantified the exact effect of Ozempic and other GLP-1 agonists on fertility. So, we can’t say for sure what percentage of women taking them are likely to become pregnant in a certain timeframe.
But we do know that it’s happening — and have some solid theories about why. 1214-P: Prepregnancy Use of Glucagon-Like Peptide 1 Receptor Agonists .... Effects of pre-pregnancy GLP-1 RA use on pregnancy outcomes, including gestational weight gain (GWG), are poorly understood. GLP-1 receptor agonists, reproductive health, and the evidence gap in .... The rapid rise of glucagon-like peptide-1 receptor agonists (GLP-1RAs), including the recent dual GLP-1/glucose-dependent insulinotropic peptide (GIP) receptor agonists, has transformed the management of obesity. Landmark trials in the STEP and SURMOUNT programmes have established semaglutide and tirzepatide as highly effective treatments for weight reduction, treatment of cardiometabolic risk ...

Can I Take My GLP-1 Medication While Pregnant?. No—GLP-1 medications are not currently recommended during pregnancy. What Are GLP-1 Medications? GLP-1 receptor agonists are a class of medications originally developed to treat type 2 diabetes.
They work by mimicking a hormone called glucagon-like peptide-1, which helps regulate blood sugar, slow digestion, and reduce appetite. However, no Glucagon-like peptide-1 receptor agonists are currently approved for use during pregnancy. GLP-1 Medications and Fertility: What to Know Before Pregnancy - WeNatal. The challenge: because GLP-1s are not considered safe during pregnancy, timing becomes critical. Moreover, for some patients, we use GLP-1s to help regulate weight and metabolism in the months before they begin trying to conceive, then transition to other therapies like, ovulation-induction medications (letrozole or clomiphene), once they discontinue. Prevalence of GLP-1 medication exposure prior to, during, and after ....

During pregnancy, the most common GLP-1 medication exposure was dulaglutide (55/80) followed by liraglutide (18/80).

📝 Summary
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