frameshift variant definition represents a topic that has garnered significant attention and interest. Frameshift Mutation - National Human Genome Research Institute. A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.
Definition of frameshift variant - NCI Dictionary of Genetics Terms. frameshift variant (FRAYM-shift VAYR-ee-unt) An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence. Frameshift mutation - Wikipedia. A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three.
Frameshift Mutation – Definition, Types, Causes, Examples. A frameshift mutation is a genetic alteration caused by the insertion or deletion of nucleotides in a DNA sequence, which shifts the reading frame of codons and results in the production of an altered and typically nonfunctional protein.
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