from genes to clinicalmanagement a comprehensivereview of represents a topic that has garnered significant attention and interest. Fromgenes to clinicalmanagement: A comprehensivereview of long QT .... Long QT syndrome (LQTS) is a rare cardiac disorder characterized by prolonged ventricular repolarization and increased risk of ventricular arrhythmias. This review summarizes current knowledge of LQTS pathogenesis and treatment strategies. Background: Long QT syndrome (LQTS) is a rare cardiac disorder characterized by prolonged ventricular repolarization and increased risk of ventricular arrhythmias. Gene and cell therapy of human genetic diseases: Recent advances and ....
This review traces the origins and evolution of these therapies, from conceptual ideas to practical clinical applications, marking a significant milestone in the field of medical science. Usher syndrome – a comprehensive review of its genetics, clinical .... Genereviews is a comprehensive resource that provides in-depth information on the genetics, clinical features, diagnosis, and management of genetic disorders. It is an invaluable tool for healthcare professionals and researchers interested in Usher syndrome type 3 and other genetic conditions. Rhabdoid Tumor Predisposition Syndrome : A Comprehensive Review of ....
This review comprehensively examines the genetic basis, clinical manifestations, surveillance strategies, and current management approaches for RTPS, with particular emphasis on emerging therapeutic options and the importance of multidisciplinary care. Comprehensive Review on the Clinical Impact of Next-Generation .... We performed a comprehensive literature review to identify recent English language publications that presented progression-free survival (PFS) and overall survival (OS) of patients with advanced cancer receiving NGS testing. Prevention, diagnosis and clinical management of hereditary breast ....
The clinical management of patients with hereditary BC, particularly those with gPVs in genes other than BRCA1/2, is a complex task. In this context, this complexity underscores the urgent need for guidelines based on recent evidence to ensure effective and personalised patient care. Objectives: The purpose of this study was to provide an in-depth understanding of LQTS genetic and molecular mechanisms, discuss clinical presentation and diagnosis, evaluate treatment options, and highlight future research directions. Clinical Utility of an RNA-based Gene Fusion Assay in ... Background Sarcoma represents a diverse group of over 70 subtypes with overlapping morphological and immunophenotypic features, often leading to diagnostic uncertainty.
Gene fusions are commonly associated with specific sarcoma subtypes and can aid in diagnosis and management. RNA-based next-generation sequencing (NGS) enables sensitive detection of gene fusions, particularly in cases with ... Equally important, innovative gene engineering and drug delivery systems for dendritic .... In this regard, our review presents a comprehensive analysis of the key tumor-generated factors that induce multiple forms of DC dysfunction in the TME.
We further highlight the recent advances in gene editing technologies aimed at engineering DCs to overcome tumor-induced dysfunction and augment their capacity for T cell activation.
📝 Summary
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